![]() ![]() Despite the role played by Msx1 in inhibiting muscle differentiation, nothing is known of the mechanisms that support the expression of the Msx1 gene within limb bud muscle precursor cells. It is thought that Msx1 may facilitate distal migration by delaying myogenesis in these cells. Msx1 is expressed in muscle precursor cells of the limb bud that also express Pax3.
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